Category:Chronos

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Chronos Scheduling Software
Application Type
  Software
Application ID
 
Description
  Chronos Scheduling Software
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Contents

Chronos Scheduling Software Overview

Most chromatographic or spectrometric investigation processes in the area of instrumental analysis are characterized by the use of autosamplers. The purpose of automation is to increase throughput without the need for additional personnel. Up to now, the samples have been worked through automatically in sequence. This means that with conventional machine control systems, waiting times frequently occur due to sample preparation during which the chromatographs are not used, offering considerable potential for throughput optimization. And it is precisely this potential which is utilized by the new Chronos software. Chronos increases the active measuring time of the machines and therefore considerably raises the efficiency of the laboratory.

The new Chronos software organizes parallel processes for sample preparation. This utilities the analysis system to a much greater extent, while observing the time margins of each individual sample preparation. To this is added further strengths of the software: a user-friendly interface minimizes the number of parameters which need to be changed depending on context. The relevant values are recorded in tabular form and can be changed by the user, which means that a complete sample list can be generated conveniently in only a few steps. Fixed parameters can be changed as needed in the method editor.

A graphic representation of the sample processing is created at the touch of a button, which means that overall duration and current progress can be followed in real time. Multi-stage sample preparation procedures can be parallelized by means of an integrated algorithm. Here also, it is possible to call up a graphic representation of the sequence of events. Chronos also combines the sample list for the autosampler control with the data system list, so that the user only has to administrate one list. This simplifies handling and avoids errors which could be caused by confusing different items.

Chronos is supplied as standard with ready-made modules for the usual analysis procedures; this includes headspace, liquid injection, SPME and other standardized methods such as for example hydrocarbon determination according to DIN H53. If required, the user can generate modules in Chronos adapted to his own needs. PAL series autosamplers from the company CTC Analytics and LEAP Technologies are currently supported.

Xcalibur from Thermo Scientific and ChemStation from Agilent are also integrated. Linking of further data systems is in process.

Axel Semrau® has developed this software in cooperation with the University of Bochum. The combination of professional programmers and IT specialists with experienced chemists who have close contact with customers is a guarantee for a practical solution of the very highest quality.

Key Benefits and Functionality

  • Chronos not only exchanges information with other systems, but also controls complete processes and optimizes intelligent time-management resulting in significant improvement in system throughput
  • Single Sample List Control - includes Twin Pal
  • Import and export of sequences in ChemStation and Xcalibur or CVS format
  • Support for liner exchange in a ATAS Linex system
  • Programming of Valco valves over a serial interface
  • Management of multiple sample lists
  • Management of priority samples
  • Call up external programs for data interpretation from within the method
  • Reading of gravimetric data from a Mettler balance
  • Support for dilutors for sample dilutions
  • Support for SPME fiber changer
  • Support for ITEX functions
  • Control of multiple PALs

Examples of Applications

GC and GC/MS

  • Headspace
  • SPME
  • ITEX-2
  • Derivatization
  • Automatic H53-extraction

Specifications

Applicable Chromatography and MS Data Systems at this time from LEAP Technologies

  • Thermo Electron Xcalibur 1.4 and 2.0 LC, GC
  • Agilent GC/LC and MSD ChemStation
  • CTC PAL Samplers
  • HTS, HTC, Twin PAL,CombiPAL, GC PAL

The simultaneous control of multiple PAL's or a Twin PAL can be realized with Chronos

System requirements: Minimum Pentium III, 1.3 GHz, Windows XP, Windows Vista; for each PAL 1 serial port (RS 232) or over network


Chronos optimizes the complex work flows of the CTC PAL and reduces waiting times of all components in GC(-MS) systems. This is possible because Chronos through its intelligent algorithms allows parallel handling of multiple samples without compromising precision and accuracy of the final results. This replaces the usual concept of serially processing samples. Chronos introduces an innovative way to enter the world of parallel, staggered sample centric work flow that raises efficiencies significantly.


Other Reference Material

Chronos Brochure









































































































Other Reference Material

Chronos Brochure



Chronos Mastersoftware is an ideal solution for automating complex sample preparation steps on the CTC PAL. Software Integration with data systems such as ChemStation™ or Xcalibur™ assures seamless functionality with existing systems. Chronos not only exchanges information with other systems, but also controls complete processes and optimizes individual work steps with intelligent time-management resulting in significant improvement of system throughput.


Videos of PAL


LEAP's PAL Application Videos on YouTube


 ↳ leaptec.com  ↳ leapwiki.com

LEAP Technologies provides fully automated sample processing workstation instrumentation solutions based on the LEAP CTC PAL X, Y, Z syringe only autosampler robot. This extremely flexible, precise, and adaptable liquid handling robotic platform is available in a variety of lengths and options depending on the requirements of your sample preparation and injections for your UHPLC, LC or GC chromatography. LEAP also offers process control systems and stand alone workstations. LEAP is an open, neutral resource for technical support of existing PAL. Keep your PAL in peak working order LEAP offers full support and service for the PAL platform with over 11 years of history with the PAL. LEAP can also write custom macros, cycles, and scheduling software for your specific applications. We're proud that LEAP is known as a productivity improver for laboratories including government labs in agencies such as FDA, USDA, EPA, FBI, Armed Forces, Homeland Security and others function more efficiently. Robotic sample prep equipment works well in government labs and challenges lab technicians to keep feeding those more samples. Analytical equipment such as chromatographs and mass spectrometers are expensive devices and also expensive to maintain. LEAP can help to keep them running and analyze samples around the clock. LEAP has most of its laboratory automation robots under GSAcontract and is eager to service and maintain everything it sells to keep your expensive lab equipment running around the clock. CTC Analytics Combi PAL and HTS PAL for Front-End Automation for LC and GC applications. LEAP offers customized on-site training. LEAP Is continuing to develop FAQ, Solutions, Tips & Techniques,a Learning Center with the LEAP Wiki for the benefit of all PAL Platform Robotic users. We will continue exceeding customer expectations for quality, cost effective and efficient results using the most current technology and expertise in our industry. Our aim is to be the ultimate knowledge base on everything related to the PAL. LEAP is known as the autosamplerguys being in business over twenty years. LEAP has extensive multi-vendor experience with integrating the PAL. HTX, HTS, HTC, HTX-xt, HTS-xt, HTC-xt, LC-Mini, Combi PAL,COMBI-xt PAL, and GC PAL models. We have the Quality, Training, Parts availability, Infrastructure, and Experience.LEAP is sometimes referred to as an Application Automation House who is continually adding new products and solutions to its Lab Automation line. As we do so we change the content of this web site so please check back.
Please contact LEAP Technologies on how we can help you get maximized throughput with flexible pipetting automation solutions whether it is our standard applications or customized to your needs. The Combi-xt PAL autosampler is able to perform liquid and headspace analysis. Headspace options include Solid Phase Micro-extraction (SPME) and ITEX-2 as alternative to purge and trap. The HTS-xt PAL autosampler dramatically increases sample throughput by offering automated sample prep, Peltier cooled and heated sample storage using the cooled stack, Peltier cooled and heated sample storage using the cooled stack and low carryover due to the self-cleaning DLW (Dynamic Load and Wash) module and L-Mark syringes, peltier cooled valves and columns. LEAP provides automation that fits your needs and reduces errors, increases sample capacity, increases efficiency, reduces cost by supplying long term productivity improvements with user friendly software and flexible hardware. LEAP performs just in time or on time sample prep and inject. LEAP offers full support of integrated and non-integrated PAL software with both sales and support for Cruise Control, Cycle Composer and Cycle Composer Macro Editor, Agilent ChemStation CTC Control, Mass Hunter and EZChrom CTC integration, Xcalibur, Waters Masslynx or Analyst CTC Control software, Thermo (Finnegan) XCalibur, LEAP Shell, and Chronos software. The PAL is more than just an autosampler, it is a high-quality and efficient laboratory robot platform that can be customized by LEAP Technologies to meet your specific needs.

Contact LEAP

Contact LEAP

For additional information about LEAP and the PAL Platform, please contact LEAP Technologies.


The information and references contained in this web site are believed to be accurate and the most current information available.

Most chromatographic or spectrometric investigation processes in the area of instrumental analysis are characterized by the use of autosamplers. The purpose of automation is to increase throughput without the need for additional personnel. Up to now, the samples have been worked through automatically in sequence. This means that with conventional machine control systems, waiting times frequently occur due to sample preparation during which the chromatographs are not used, offering considerable potential for throughput optimization. And it is precisely this potential which is utilized by the new Chronos software. Chronos increases the active measuring time of the machines and therefore considerably raises the efficiency of the laboratory.

The Chronos software organizes parallel processes for sample preparation. This utilities the analysis system to a much greater extent, while observing the time margins of each individual sample preparation. To this is added further strengths of the software: a user-friendly interface minimizes the number of parameters which need to be changed depending on context. The relevant values are recorded in tabular form and can be changed by the user, which means that a complete sample list can be generated conveniently in only a few steps. Fixed parameters can be changed as needed in the method editor.

A graphic representation of the sample processing is created at the touch of a button, which means that overall duration and current progress can be followed in real time. Multi-stage sample preparation procedures can be parallel by means of an integrated algorithm. Here also, it is possible to call up a graphic representation of the sequence of events. Chronos also combines the sample list for the autosampler control with the data system list, so that the user only has to administrate one list. This simplifies handling and avoids errors which could be caused by confusing different items. All encompassing functionality

  • import and export of sequences in ChemStation and Xcalibur or cvs-format
  • control of multiple PALs
  • support of Dual PAL systems
  • support for liner exchange in a ATAS Linex system
  • programmability of Valco valves over a serial interface
  • customizable sample list for easy user interface adjustments
  • management of multiple sample lists
  • management of priority samples
  • call up external programs for data interpretation from within the method
  • reading of gravimetric data from a Mettler balance
  • support for Gilson dilutors for sample dilutions
  • support for SPME fiber changer
  • support for ITEX functions
  • support of 2D bar code reader
  • ability to send SMS messages
  • control of peristaltic pumps for liquid handling


Examples of Applications

GC and GC/MS

  • Headspace
  • SPME
  • ITEX-2
  • Derivatization
  • automatic H53-extraction
  • on-line SPE
  • Dual PAL applications

HPLC and LC/MS

  • multi-dimensional chromatography
  • matrix separation using SPE
  • derivatizing with fluorescence tags
  • fast separation of active ingredient in pharma research

Chronos is supplied as standard with ready-made modules for the usual analysis procedures; this includes headspace, liquid injection, SPME and other standardized methods such as for example hydrocarbon determination according to DIN H53. If required, the user himself can generate modules in Chronos adapted to his own needs. PAL series autosamplers from the company CTC Analytics and OEM products of the same design are currently supported.

Xcalibur from Thermo Scientific, Chemstation from Agilent and Analyst are also integrated. Linking of further data systems like EZChrom is in process.

H53 Workstation The determination of the hydrocarbon index in water is now predominantly by GC-Use / according to EN ISO 9377-2 / DIN H 53rd We offer our customers the opportunity to complete this analysis, therefore, to automate the steps, extraction, phase separation, extract purification, concentration and GC analysis.

The H53 Workstation is a complete workstation for this task. It consists of the components CombiPAL, Optic2, Trace GC

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