Measuring nicotine partitioning from a tobacco smoke filter pad in an ammonia environment


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A Twin PAL [1] is used to measure nicotine partitioning from a tobacco smoke filter pad in an ammonia environment.
Filter pads that have collected tobacco smoke will be placed in 20ml vials. A zero-analysis will be performed by the SPME PAL.
Then the Prep injection head will add 5 to 40mls [2] of ammonia to the sample vial using a 5ml syringe and the vent tool[3].
After the sample equilibrates, the sample vial will be placed in the agitator [4] and SPME [5] analysis will be performed.
This process of flushing the sample vial with ammonia and then performing SPME [6] analysis will be repeated for a number of iterations determined by the operator.


Project Ref: T1024

  • Additional info on SPME [7]
  • Additional info on Mixing of Samples [8]
  • Additional info on Fiber Conditioning Station [9]

For other cost/time saving measures consider:

  • “Look Ahead”, sample prep before injection (M-004) using LEAP Shell Software [10]
  • Chronos Software and application for custom GC injections and scheduling [11]

Videos of PAL

LEAP's PAL Application Videos on YouTube

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LEAP strives to find total solutions for analytical lab automation by automating analytical processes for small and large molecules in extracted liquids, solids, and recently in human, animal and plant tissues. We provide the precise robotics and efficient sample prep required by modern measurement techniques such as MALDITOF mass spectroscopy. Our newest specialty customization of CTC Analytics’ PAL features small workstations that can perform complex liquid handling tasks including HPLC-Purification, SPE, filtration, weighing, heating and stirring. They can be configured as stand alone units or integrated for “just in time” sample prep for LC-MS or GC-MS analysis.
LEAP provides automated workstation instrumentation solutions based on the LEAP CTC PAL X, Y, Z syringe only autosampler robot from LEAP Technologies. This extremely flexible, precise, and adaptable liquid handling robotic platform is available in a variety of lengths and options depending on the requirements of your sample preparation and injections for your UHPLC, LC or GC chromatography.LEAP offers full support and service for the PAL platform in addition to being able to write custom macros, cycles, and scheduling to your applications. Please contact LEAP Technologies on how we can help you get maximized throughput with flexible pipetting automation solutions.

Contact LEAP

Contact LEAP

For additional information about LEAP and the PAL Platform, please contact LEAP Technologies.

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