ITSP cartridge
From LEAP
| Sample Filtration |
| Application Type | |
| SPECIAL | |
| Application ID | |
| ITSP | |
| Description | |
| Sample Filtration with ITSP System of Microliter Inc. |
Contents |
Overview
ITSP (Instrument Top Sample Prep) for Serial Solid Phase Extraction (SPE) or Sample Filtration uses a standard PAL syringe as the solvent reservoir for Microliter's disposable SPE cartridges. The combination replaces expensive dedicated SPE liquid handlers and cumbersome or inconsistent vacuum manifolds. Pressurizing multiple wells is eliminated, no loss of samples or inconsistency of extraction due to leaks or loss of vacuum. Furthermore standard SPE liquid handlers require a manual transfer of the extracted samples to a sample injector. Since the PAL itself is a sample injector this can be avoided using the automated ITSP – PAL combination. ITSP for PAL Systems is distributed exclusively by Microliter Inc.
Significant Markets
Any labs who are doing High Performance Liquid Chromatography (HPLC) or more significantly, Ultra High Performance Liquid Chromatography (UHPLC) analysis. It is imperative that particles are eliminated to avoid blockage of HPLC lines and columns.
Brochure
ITSP Sample Prep Automation Guide
Video
Movies of ITSP on PAL in action.
Video from Microliter on ITSP with Quicktime
Example Application Notes
Determination of Cocaine and Benzoylecgonine in Human Urine Using Automated ITSP Solid Phase Extraction and Liquid Chromatography Mass Spectrometric Detection
ITSP Extraction of Cortisol from Plasma
Autosampler-Based Sample Preparation for Just-in-Time Extraction of Tacrolimus, Sirolimus and Cyclosporine for LC/MS Analysis
AMHSA-5_Drugs_of_Abuse_ITSP_Application_Notes
Automated SPE-LC/MS/MS Assay for 25-OH Vitamin D Metabolites from Serum
Determination of Vitamin D Metabolites in Human Serum Using Automated ITSP Solid Phase Extraction and Liquid Chromatography-Tandem Mass Spectrometry
Development of a SPE/DART Assay for Rapid Narcotics Screening in Urine
ITSP Hardware Kits and Accessories
ITSP Hardware Kits offer you the proper hardware components to manage ITSP. Included in each kit is the Prep Tray, Waste Receptacle, a Needle Guide and a replacement screw for the LC inlet.
If you are using ITSP for Solid Phase Extraction you may also need additional software, solvent reservoirs, a fast wash station or other sample trays. In this section you will see a variety of solutions for these additional needs.
LEAP provides automated workstation instrumentation solutions based on the LEAP CTC PAL X, Y, Z syringe only autosampler robot from LEAP Technologies. This extremely flexible, precise, and adaptable liquid handling robotic platform is available in a variety of lengths and options depending on the requirements of your sample preparation and injections for your UHPLC, LC or GC chromatography.LEAP offers full support and service for the PAL platform in addition to being able to write custom macros, cycles, and scheduling to your applications. Please contact LEAP Technologies on how we can help you get maximized throughput with flexible pipetting automation solutions.
