Monitoring of Microorganism by-products

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Monitoring of Microorganism by-products
Application Type
  Process Monitoring
Application ID
  ProcessMonitoring1001
Description
  Timed sampling of bio-reactor vessels

Contents

Overview

The PAL application will automate the timed sampling of culture fluid from a bacterial culture vessel. The samples will be taken from up to 8 flow cells which are mounted on the PAL workspace and which will be receiving constant flow of fluid from the culture vessels using a peristaltic pump. Samples will be aspirated at specified times over a period of up to one week and dispensed into vials or 96 well plates.

Optional

  • Dosing of the cultures with nutrients or pH buffers is also possible.
  • The collected fraction may later be injected into the HPLC system using the standard “LC Inj” macro.

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Significant Markets

This application provides a tool for those labs where sampling at precise time intervals must be done over prolonged periods. This includes labs who are developing antibiotics or monitoring antibiotic resistance.


LEAP Shell Application

LEAP Shell is ideal for setting up timed sampling operations. Customized columns in the Sample List make operation very simple.

Reporting capabilities are extensive allowing real-time updates of actual sample times as well as output to logfiles and Excel spreadsheets.



Accessories for the PAL

Filtering of Samples

Bar Code Reading

Cooling &Heating Sample Storage

Large Volume Dispensing

Mixing and Heating of Samples

Other Accessories for PAL Robots


LEAP provides automated workstation instrumentation solutions based on the LEAP CTC PAL X, Y, Z syringe only autosampler robot from LEAP Technologies. This extremely flexible, precise, and adaptable liquid handling robotic platform is available in a variety of lengths and options depending on the requirements of your sample preparation and injections for your UHPLC, LC or GC chromatography.LEAP offers full support and service for the PAL platform in addition to being able to write custom macros, cycles, and scheduling to your applications. Please contact LEAP Technologies on how we can help you get maximized throughput with flexible pipetting automation solutions.

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