Sample Filtration
From LEAP
| Sample Filtration |
| Application Type | |
| SPECIAL | |
| Application ID | |
| PALPress | |
| Description | |
| Sample Filtration with Whatman Mini-Uniprep filter system |
Overview
Whatman Mini Uniprep syringeless filters offer a convenient way of filtering samples containing particulates prior to introduction on an HPLC system. They come with 2 pore sizes and may different filter substrates [1]. They are designed for manual operation but are not conducive to high throughput - repeated pressing by hand being quite fatiguing.
LEAP has developed a "Press" accessory for the PAL which allows samples to be filtered reliably and repeatably. It does not require external pneumatics, but uses the PAL Z motion itself to compress the filter chambers. Samples can be processes in batch mode or "just in time" before direct injection to the LC valve.
The PAL offers precise control of the downforce on the sample. The user can specify the speed of compression in the method, allowing even very heavy suspensions to be filtered successfully.
Significant Markets
Any labs who are doing High Performance Liquid Chromatography (HPLC) or more significantly, Ultra High Performance Liquid Chromatography (UHPLC) analysis. It is imperative that particles are eliminated to avoid blockage of HPLC lines and columns. This filtering technique let you prepare samples in one third the time required by other methods. Automation of the filtering step has NOT been possible in a reliable fashion till now.
