Dual Channel Sample Cleanup
From LEAP
General Description of process:
Samples are injected and pass through a guard column which is in-line with the analytical column. At a specified time, the guard column switches out of line and is regenerated using a wash pump configured to do a step gradient while the sample peaks are acquired.
To increase throughput, samples are injected ahead of the acquisition time, so that pre-filtration is occurring concurrently with the previous samples acquisition. Each line of the sample list processes a pair of samples which are staggered in this way.
4 pumps are required: - 2 wash pumps (Agilent 1200) pre-programmed to perform the step gradient and 2 isocratic analytical pumps running continuously one for each column.
Project Ref: H1073b
For other cost/time saving measures consider:
- LEAP offers multiple choices of Valve Self Wash Stations to aid in cleaning the valve [1]
- “Look Ahead”, sample prep before injection (M-004) using LEAP Shell Software [2]
- Dual Channel Parallel Injection (M-005) using LEAP Shell software [3]
- Summary of LC Multi Valve Applications [4]
- LEAP Shell Software and application for custom injections and scheduling [5]
Contact LEAP
For additional information about this technique please contact LEAP Technologies for detailed information
