Micro Extraction by Packed Sorbent
From LEAP
| SPE Applications |
| Application Type | |
| STANDARD AND SPECIAL | |
| Application ID | |
| MEPS | |
| Description | |
| Micro Extraction by Packed Sorbent (MEPS) |
www.leapwiki.com
Contents |
Overview
Micro Extraction by Packed Sorbent* (MEPS) is a new development in the field of sample preparation by solid phase extraction (SPE), and is a result of a collaboration between SGE and Mohamed Abdel-Rehim (AstraZeneca) and Lars G. Blomberg (University of Karlstead) Automation of MEPS is accomplished with the PAL Series of CTC Autosamplers. MEPS is the miniaturization of conventional SPE packed bed devices from milliliter bed volumes to microliter volumes. The MEPS approach to sample preparation is suitable for reversed phases, normal phases, mixed mode or ion exchange chemistries. MEPS is available in a variety of common SPE phases. The cartridge (Patent Pending) contains the stationary phase, and is built into the syringe needle. With a typical void volume of a few μL, the MEPS elution is compatible with GC and LC inlets making it ideal for automated on-line SPE on the CTC PAL platform. MEPS kits are exclusively available worldwide through LEAP Technologies and SGE Analytical Science.
MEPS performs the same function as SPE, namely the purification or speciation of samples, but with some significant differences:
- MEPS works with much smaller samples (as small as 10µL) than full scale SPE
- MEPS can be fully automated – the sample processing, extraction and injection steps are performed on-line using the same syringe
- MEPS is applicable to GC and LC
- Significantly reduces the volume of solvents and sample needed
MEPS online is an SPE solution for rapid development, in a variety of matrices; plasma, serum, whole blood, urine, aqueous
MEPS for PAL Systems is distributed by SGE & LEAP Technologies.
Benefits of MEPS
- MEPS allows SPE methodology to be applied to small sample volumes.
- MEPS can be integrated into autosampler robotics and allows on-line use of SPE.
- MEPS can reduce sample and reagent consumption and waste disposal.
- Double pass flows can reduce the weakly bound fraction.
- MEPS is field portable for remote sampling with or without the use of automated equipment.
- MEPS is adaptable for other analytical techniques including immunoassay and off-line analysis by NMR, IR and other methods.
Available for both GC & LC applications. There are over 65 pre-set methods.
Significant Markets
- Natural Products
- Environmental
- Food & Beverage
- Pharmaceuticals
Sample Methods
- Aflatoxin B2 and M2 Metabolite
- Amphetamine
- Catecholamines
- Cyclosporin
- F-2 Mycotoxin
- Opiate Anagelesics
- Phthalate Esters
- Prostaglandins
- Persistent Organic Pollutants (PAH, PCB, and Pesticides)
- Steroid Acids
- S-triazine Herbicide (Atrazine)
- Vitamin A, D, and E
Photos
MEPS and CTC Autosampler for LC and GC |
MEPS Syringe |
Process of MEPS |
 MEPS Kit |
 Information specific to MEPS for CTC Autosamplers MEPS Online – The SPE solution for your CTC platform |
More Info
MEPS web site by SGE including product brochure
www.leapwiki.com
Contact LEAP
For additional information about this technique please contact LEAP Technologies for detailed information
